Opioids and Antagonists

Summary table of common opioids

Another summary table of opioids (contribution by BJS et al)

Pharm-18B5 List the desired and adverse effects of opioids and the corresponding anatomical location of the receptors being activated. (also Pharm-16B12)

Pharm-17B15 Write brief notes on the pharmacology of tramadol. (also Pharm-04B4)

Pharm-16A5 Discuss the relative advantages and disadvantages of using morphine versus fentanyl for post-operative Patient Controlled Analgesia (PCA). (also Integrated-15A11, Pharm-11B6)

Pharm-14A10 List the pharmacodynamic differences between tramadol and morphine

Pharm-13A08 Discuss the metabolism of morphine, codeine and pethidine

Pharm-12B04 Outline the acute adverse effects of opioid receptor agonists. Describe the mechanisms of the acute adverse effects of opioid receptor agonists. 55% (Also Pharm-05A2,Pharm-98B11)

Pharm-11A6 Write a brief outline on the pharmacology of remifentanil. (also Pharm-99A10)

Pharm-10B1 Compare and contrast the pharmacokinetics of orally and intravenously administered morphine and oxycodone.

Pharm-09A5 Outline the effects of an opioid injected into the spinal intrathecal space (also Pharm-04A4,Pharm-01B12).

Pharm-07B3 Outline the important pharmacological considerations concerning choice of opioid and dosage when converting from intravenous morphine to oral opioid analgesia in the post operative period.

Pharm-06A7 Briefly outline the pharmacology of naloxone.

Pharm-03A6 Explain how differences in the pharmacokinetics of alfentanil and fentanyl can influence the way they are administered intravenously. 51% (also Pharm-00B12)

Pharm-02B6 Write brief notes on tolerance and dependence in relation to opioid analgesics.

Pharm-00A15 Describe the effects of opioids on the respiratory system 75%

Pharm-96B9 Briefly explain the factors which determine the duration of effect of intravenously administered bolus doses of fentanyl. 70%

Pharm-96A11 Describe briefly the pharmacokinetics of pethidine. 60%

1993 Discuss the advantages and disadvantages of administering narcotics by intermittent injection or by infusion.

1992 Write short notes on the cardiovascular effects of narcotics

1991 Write short notes on narcotics administered via the epidural route

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