Pharm-17A8 Compare and contrast low-molecular-weight heparin and unfractionated heparin.
Pharm-14B8 Outline the important pharmacological considerations when stopping warfarin and commencing prophylactic (low dose) low molecular weight heparin (LMWH) in the peri-operative period. (als0 Pharm-07B2)
Pharm-12B01 How does warfarin exert its anti-coagulant effect? What methods can be used to reverse the effects of warfarin prior to surgery? 64%
Pharm-11B5 Describe the mechanism of action of protamine when used to reverse the effects of heparin. Outline the side effects of protamine. (also Pharm-95A8)
Pharm-08B7 List the agents used to therapeutically reduce platelet function. Outline their mechanism of action, adverse effects, mode of elimination and duration of action. (also Pharm-05A5)
Pharm-04A8 Describe briefly the side effects and complications of heparin therapy. (also Pharm-95B4)
Pharm-02A15 Describe the mechanism of the anticoagulant effect of coumarin derivatives and what determines the onset and offset of action.
Pharm-99A15 List the drugs used clinically as anti-coagulants and anti-thrombotics. Write short notes on the mechanisms of their actions. 65%
Pharm-95A10 Outline the importance of vitamin K and the factors determining its uptake.